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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64760c51dff191b3801c7c3059be078fe0db57f403a4e362166ae4c3e355a2fb' 
  AND token = 'c2mRONInPROiVVUGyN3ekAMMxb0/K9GFr+StPKFQ8C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}