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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fd0afdbca172d8e591ee2b25af7b75457d9e8de765dd42b380ed05a49fd8aa' 
  AND token = 'NJTYsfrlkTYh7QYZbkmcIHZedVkWTEGpak4WSnh6dwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}