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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c33aacfaecb110451a0e9e2b670cd211f1e7fc68b3a9d131ca4405598453f5b' 
  AND token = 'k4WW6sw/PvhOXSsES0ZDrQqqGrF2zkK19sjVsDa8CRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}