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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd272d0d4230f69c032e2b99490e9cd09d10aecf00a4f57a722bc2db711190d85' 
  AND token = 'T4mCvR1d2aniYfbZgdSZBeVsuZ2VEX/uXVaHoTQZfSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}