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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed749c791369e47fd74175a7d22b9b2f4117f2eeff9f38ac289dd5c8abefc70' 
  AND token = 'yJZgOr8m/3LovmpRiyexZazFEYd5NvKLsJmrDsBeiDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}