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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f47e7535cea2af5a63b545e0a365fceb8295264dffb3974ae643abb811e764' 
  AND token = 'JhFNo4XZd2VMRdntiNOM2YKYMHSuvrBR4JsONFWVNPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}