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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821c89e3e2e922f1dfe29cc52bc6a5a58a705a6eaf3f1568a01a65d86b1e4120' 
  AND token = '2DHmosPqmFx4WZurYMdjAM5qBPiOk8lOgpQ5tOZNXHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}