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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67bf67fa3e63c2c667021ec9c2947af9f48b068494c1ee41e8c006fc973f534e' 
  AND token = 'fOIOIlCvG9YJ76kiW/EmhiyYU4IXGuf2XJTB3vF9lr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}