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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3845cc1b581406d9cb44852752ee6d5aa171d95ba5c377be5976460c6b2e09c' 
  AND token = 'fP/PlAqndrdTYBIxGoEwwVIlbfBR3a+kttNtDtSmBI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}