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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40c5a289ca664a65e1016808d32703a7e21f8f292cd0fdafa4e2ca1ddb90a435' 
  AND token = '0Wuqvt1O25xi5tN34Njb9ijh1fwTOoZtbHAVMJ718eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}