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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df0817d4be2a2b63eb44238e69a35eac7567caaf34ab8076073d10974b6d1d53' 
  AND token = 'QWV44r98Ua/zx6mkTrVx9Qpn0Gi9wjU6neTNDmSmj94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}