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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343f0bed5e7c185462425666b6e0d44bb9d6b512748fa1cab4eb984225b8298d' 
  AND token = 'u4po7Lnmb0PyZ3bZSe0MNStdhEFrpo3qiGEFMnB5r7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}