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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20dae043344bd8a870fe6913cb22ea2c016d251a5c147c503961ca0234b72422' 
  AND token = 'Ilbu3XYLGrvl3muEgrSBZnILNJfyGwFEzM8rOxU9fcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}