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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a149c4e487511d8a5da5e1c4cfa3a53f1ad79421bb430ccf9985e800c2400430' 
  AND token = 'BKtE5U08Ril/l9142eMgHa9QCxNDIS0etChjkur52I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}