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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d83d66c50cf5509be2af3f796ec4d0b23454f992cbdfb105c82a9de5e381d4f' 
  AND token = 'jRo6YGAb0fq0/cmLPQiPh4UfMWrf4H/NFzrYgtJy1Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}