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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78d3cac906a8800f6d867e436ba4af24997ee08457a03f6611f8a1002247b49' 
  AND token = 'hI8VQ1ft46/w6mBTdEJ22TfYr85vL+fsm0J4CdtR6OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}