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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9455e6b6033d3de693e821fde85de9b0ce5558acf145601765d71d050cd854ea' 
  AND token = '8AWwM5AzaP3zkw+QeeDkvwrBbhTSbFpiIMNe4nR/l5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}