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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64029026948c4e71861cd6bf043226210721db4bc306aec3f754f400e69f4220' 
  AND token = '7Fvbth/mnQiibPW4rCYccSL+1ON9K2iNvcpkHd9I3cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}