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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec9052185fd5ba790e846326c873b36eef22ce28572a0e45736404dcd03cda8' 
  AND token = 'yz0v9Fu4oTiBwuww5K6Y7B6MrTVdYXhm8XSC55t3uqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}