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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2bcb55a73a31a7561e2c6e8fff525f0e053d548a27f5ae4c50e602c2373def3' 
  AND token = '6ZaWQ7IyDrR0wUeVsWnLz9Chk6sVkgXFRorBJnOCQ14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}