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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db9a1363e98bb1bf4475ee47f945978adbac2c40b43b2bc60db315ce4e6633f' 
  AND token = 'sNZUnDQ3N14G/J7t3vdmb5JSSK3c4zb5F4P05lt5040=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}