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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40395555ab336900184da9613a956f7938851685a1f2ab57a04fa8765021e275' 
  AND token = 'g9eXjyLobGE23NfEcxqA7oC4/GaDnQKL6+1hGnZSbI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}