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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ad1f1fd0f8ed25cbfdae018f3af1ca2a54f7c16a56e84fbe6214d939e9b4c9' 
  AND token = '82kflj5HgdMWlFsPYIk1BL7PXPx/EcJ9f8fAQCsc0Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}