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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481d381c7c08b222510f8fecdd957cc221b5b3e9aae53e4672095f2408229faf' 
  AND token = 'IDriNNnw1DNCx9SC++OD8jq1U6mJJn7drI4Em6KasYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}