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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2958afe2192937f18368b656a7de8a09dce7992c4ddf7ca215a609dde0a2d8' 
  AND token = '5C0GiMWcXSntEVJi9yx0vPjDNwAqdkG3CQxfjTlIt30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}