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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4e1674a8904f9a8c58a525ebd59351c7d8fc30c811416b8079a16dfb8f8572' 
  AND token = '1DSWJChPly4u0Q4yTvbOC6BvVgNhNv+pij02rcCtiSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}