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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0e4357d1eb2aa6552c3a5760827c4e326da2b0a46308dbb493a364a9cd3c72' 
  AND token = 'Gzs9evXe8aVaQrPMPb4zx5/GD3Ml5x/4l1IN17ycfnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}