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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '506e5658b7568087c41b4c1924bb20b3029002fe13052d40a3e243e7ab22f014' 
  AND token = 'Gt+giC0LAgldlQuNH+oxR+La7CeWL1mvxh57Lgox5vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}