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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26b0040298bb08e0ea7fb3a7365af0bb784ca8821907b41f40d9811eb6ad900d' 
  AND token = 'cNcdLFHmpIgFfQUMP97A/M2SlnK23K2d8+EbdK8Yz2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}