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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ac7b9e93d7460cb02de7fa998f2921c56fb7752783139596ff198f275b55110' 
  AND token = '1GGR2dT8M1FRSi10B8xcdUly7zedFRHXGIWVTY4vaN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}