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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7da55396c60ad37691512a8cfbeb5162e5fab60a1dc5e63d4eaa015c3429f242' 
  AND token = 'ZxklKRLakc1VzhBGYcojFtz4Q5wfhcFU25nsv28UcKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}