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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e38a242d1ae1cceaf11a4a60c9e92d1e30269c9d8b6aaa6f845095e7234d1a7' 
  AND token = 'Tz8cU9eLfW/adVM/A6TlHxZXNSMYicvSKjhULq0Mi5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}