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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84d2e4a82b38ca8ba8c6cb4a0999341530329047d39ebd5048df6ca4c8480382' 
  AND token = '+okr+V/iCakRTsEB+1fYAT1bt3a9AsLxXmrVKb3wsf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}