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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458be3bc670096625a04dd6d15c864b8210e902fae95ddb33c29ab1a0102cc42' 
  AND token = 'VHfMaAW4PzxYU8jYWn3Uc5poTc37fbDX/6ksR0/TDWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}