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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ca343618959ba1ea64b0acd63d5a3b195ea18a1154c6c4d8639d72ac6bca78' 
  AND token = 'jIBP5XGsTJ2zc6ddLQtiujt7UXTPMnrw/qvE3CWml0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}