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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc972fd39b47359a3d3c411b71df0526cd0c99c3abd1037042ebe77f5f0af6bf' 
  AND token = 'dkOZiTbFmSt4bImI6zgp3n6HCWuwPMO+O6wKSeLb3l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}