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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8603f6604fd718ffc822d8538e819c68f8914462e0e160a77b2a7bfa2030767' 
  AND token = 'LghhiFlB8Za7PGvasziAPQ6wiBv3N05b93CCAxO5MGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}