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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63d4cfe26ad5e64d4af3c3aa084c755f4021eb51d112704d66beb2977bfb0b2b' 
  AND token = 'Uxdz71a6hJyGJkDMefq6zXxkDQDzMm37wWVt7Vk0sls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}