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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e148e6023da9b9b9fd28c0dc3723bc6fd05dc06a096dc591ee56ca5324c9dda5' 
  AND token = 'E8aOvHwD6eJtsOhkDjfwWGnmTzWGB4UjI5mb9o1+Bqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}