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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e122d62c086e90181e057ed04183cb4be322c9fe8521d3b8bdaed285d30e5e8' 
  AND token = 'DGcq7+ZmVgeKCPNFkv86mTySMuIVfbrHsuBLz/In/Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}