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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1dc0616a788515a1f61b66e872bac85fe133af4f2cc05f0e8e57b4eede25c0' 
  AND token = '7dqwyR6zOQ6c7/6I3pXT17cQ8WGqhG5T5aSXYI+3xcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}