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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13abd8c226212018ea2b5d06079a660b0d866b635f74593bbc315e5d79f2f6ec' 
  AND token = 'AoGfEtCFZBc4XvXrUwPd1VkVA7x+h0HI7OEV8IXDOIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}