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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3eed69f7d9db722f675f8d993871ec6ecc1da9668ad70073ae77cb1d7e349d5' 
  AND token = 'QyAwFIq4X3T7tGUDj/dON6E8mtdTeFctcFwzsI9Pf70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}