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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51664e0d87221decc0e81e0f5b73fbf70876d772e35aa73c1a26b9535c3c92de' 
  AND token = 'EU8zoRBTJzcNEpKfYDh6+fC2Jm9FrmktJ42pR6/9uSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}