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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e296eab031104bd4c3282559e09ae0c5798d67a7200194869dfc2c75a2d04fde' 
  AND token = 'qglDITVadmnINc5j/cAx8HgPIJtoh6/wnaTMWvjWHe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}