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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '571d7e34129096489fbdfaa5dd4e42ed6c43e937b1c87b96c05c678bc47858a2' 
  AND token = 'XQFRHg8sOXatU9/GrZMS2XfyPS4xMShjN90aRKoF9hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}