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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6419336370f68e96674c5a37c1d5f456aed85f4c74c9b763e4f3bce360d024' 
  AND token = '8uIMTSPpQlIsy42cV0o1oBUO+Th9LYXcBm9gC1S9nDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}