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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc8b25c2df4fe59eccf316fa20efd6bdf60542c290174f3b1898daca2f6cf29' 
  AND token = '6Xzurpx8vFvGsUEVVMGWQzdd7TFvFDqTQDvRUKBczeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}