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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8a1aabfa3f22ab3d72b1c6c9cdcd67e68d092c4120fb5b9665c1dc58f03ea8' 
  AND token = 'YfxrCuGUDXBRvRutKQYttho9Qal6aQ7N7fvo27g0Vwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}