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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218ab24941c907d9326c8c0bb8452beb9dfae9ea46dfc4459c8cda563e0c3e7b' 
  AND token = 'I7iTmqYXbwcLM251wViBngLBT2dl4X0uQ75Y+8CSHEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}